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Preserving Genome Integrity during the Early Embryonic DNA Replication Cycles
During the very early stages of embryonic development chromosome replication occurs under rather challenging conditions, including a very short cell cycle, absence of transcription, a relaxed DNA damage response and, in certain animal species, a highly contracted S-phase. This raises the puzzling qu...
Autores principales: | Kermi, Chames, Aze, Antoine, Maiorano, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563053/ https://www.ncbi.nlm.nih.gov/pubmed/31137726 http://dx.doi.org/10.3390/genes10050398 |
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