Electron Microscopy in Discovery of Novel and Emerging Viruses from the Collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)

Since the beginning of modern virology in the 1950s, transmission electron microscopy (TEM) has been an important and widely used technique for discovery, identification and characterization of new viruses. Using TEM, viruses can be differentiated by their ultrastructure: shape, size, intracellular...

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Detalles Bibliográficos
Autores principales: Popov, Vsevolod L., Tesh, Robert B., Weaver, Scott C., Vasilakis, Nikos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563235/
https://www.ncbi.nlm.nih.gov/pubmed/31130629
http://dx.doi.org/10.3390/v11050477
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author Popov, Vsevolod L.
Tesh, Robert B.
Weaver, Scott C.
Vasilakis, Nikos
author_facet Popov, Vsevolod L.
Tesh, Robert B.
Weaver, Scott C.
Vasilakis, Nikos
author_sort Popov, Vsevolod L.
collection PubMed
description Since the beginning of modern virology in the 1950s, transmission electron microscopy (TEM) has been an important and widely used technique for discovery, identification and characterization of new viruses. Using TEM, viruses can be differentiated by their ultrastructure: shape, size, intracellular location and for some viruses, by the ultrastructural cytopathic effects and/or specific structures forming in the host cell during their replication. Ultrastructural characteristics are usually sufficient for the identification of a virus to the family level. In this review, we summarize 25 years of experience in identification of novel viruses from the collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA).
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spelling pubmed-65632352019-06-17 Electron Microscopy in Discovery of Novel and Emerging Viruses from the Collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA) Popov, Vsevolod L. Tesh, Robert B. Weaver, Scott C. Vasilakis, Nikos Viruses Review Since the beginning of modern virology in the 1950s, transmission electron microscopy (TEM) has been an important and widely used technique for discovery, identification and characterization of new viruses. Using TEM, viruses can be differentiated by their ultrastructure: shape, size, intracellular location and for some viruses, by the ultrastructural cytopathic effects and/or specific structures forming in the host cell during their replication. Ultrastructural characteristics are usually sufficient for the identification of a virus to the family level. In this review, we summarize 25 years of experience in identification of novel viruses from the collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA). MDPI 2019-05-25 /pmc/articles/PMC6563235/ /pubmed/31130629 http://dx.doi.org/10.3390/v11050477 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Popov, Vsevolod L.
Tesh, Robert B.
Weaver, Scott C.
Vasilakis, Nikos
Electron Microscopy in Discovery of Novel and Emerging Viruses from the Collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)
title Electron Microscopy in Discovery of Novel and Emerging Viruses from the Collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)
title_full Electron Microscopy in Discovery of Novel and Emerging Viruses from the Collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)
title_fullStr Electron Microscopy in Discovery of Novel and Emerging Viruses from the Collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)
title_full_unstemmed Electron Microscopy in Discovery of Novel and Emerging Viruses from the Collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)
title_short Electron Microscopy in Discovery of Novel and Emerging Viruses from the Collection of the World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)
title_sort electron microscopy in discovery of novel and emerging viruses from the collection of the world reference center for emerging viruses and arboviruses (wrceva)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563235/
https://www.ncbi.nlm.nih.gov/pubmed/31130629
http://dx.doi.org/10.3390/v11050477
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