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Fusaoctaxin A, an Example of a Two-Step Mechanism for Non-Ribosomal Peptide Assembly and Maturation in Fungi
Fungal non-ribosomal peptide synthetase (NRPS) clusters are spread across the chromosomes, where several modifying enzyme-encoding genes typically flank one NRPS. However, a recent study showed that the octapeptide fusaoctaxin A is tandemly synthesized by two NRPSs in Fusarium graminearum. Here, we...
Autores principales: | Westphal, Klaus Ringsborg, Nielsen, Katrine Amalie Hamborg, Wollenberg, Rasmus Dam, Møllehøj, Mathias Bonde, Bachleitner, Simone, Studt, Lena, Lysøe, Erik, Giese, Henriette, Wimmer, Reinhard, Sørensen, Jens Laurids, Sondergaard, Teis Esben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563249/ https://www.ncbi.nlm.nih.gov/pubmed/31100892 http://dx.doi.org/10.3390/toxins11050277 |
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