Epoxyscillirosidine Induced Cytotoxicity and Ultrastructural Changes in a Rat Embryonic Cardiomyocyte (H9c2) Cell Line

Moraea pallida Bak. (yellow tulp) poisoning is the most important cardiac glycoside-induced intoxication in ruminants in South Africa. The toxic principle, 1α, 2α-epoxyscillirosidine, is a bufadienolide. To replace the use of sentient animals in toxicity testing, the aim of this study was to evaluat...

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Detalles Bibliográficos
Autores principales: Isa, Hamza Ibrahim, Ferreira, Gezina Catharina Helena, Crafford, Jan Ernst, Botha, Christoffel Jacobus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563272/
https://www.ncbi.nlm.nih.gov/pubmed/31117277
http://dx.doi.org/10.3390/toxins11050284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563272/
https://www.ncbi.nlm.nih.gov/pubmed/31117277
http://dx.doi.org/10.3390/toxins11050284

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