Allele Loss and Reduced Expression of CYCLOPS Genes is a Characteristic Feature of Chromophobe Renal Cell Carcinoma

Copy-number alterations Yielding Cancer Liabilities Owing to Partial losS (CYCLOPS) genes have been recently identified as the most enriched class of copy-number associated gene dependencies in human cancer. These genes are cell essential and render tumor cells highly sensitive to the expression of...

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Detalles Bibliográficos
Autores principales: Ohashi, Riuko, Schraml, Peter, Batavia, Aashil, Angori, Silvia, Simmler, Patrik, Rupp, Niels, Ajioka, Yoichi, Oliva, Esther, Moch, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563336/
https://www.ncbi.nlm.nih.gov/pubmed/31200327
http://dx.doi.org/10.1016/j.tranon.2019.05.005

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