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Recognition of Amino Acid Motifs, Rather Than Specific Proteins, by Human Plasma Cell–Derived Monoclonal Antibodies to Posttranslationally Modified Proteins in Rheumatoid Arthritis

OBJECTIVE: Antibodies against posttranslationally modified proteins are a hallmark of rheumatoid arthritis (RA), but the emergence and pathogenicity of these autoantibodies are still incompletely understood. The aim of this study was to analyze the antigen specificities and mutation patterns of mono...

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Detalles Bibliográficos
Autores principales: Steen, Johanna, Forsström, Björn, Sahlström, Peter, Odowd, Victoria, Israelsson, Lena, Krishnamurthy, Akilan, Badreh, Sara, Mathsson Alm, Linda, Compson, Joanne, Ramsköld, Daniel, Ndlovu, Welcome, Rapecki, Stephen, Hansson, Monika, Titcombe, Philip J., Bang, Holger, Mueller, Daniel L., Catrina, Anca I., Grönwall, Caroline, Skriner, Karl, Nilsson, Peter, Lightwood, Daniel, Klareskog, Lars, Malmström, Vivianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563427/
https://www.ncbi.nlm.nih.gov/pubmed/30152202
http://dx.doi.org/10.1002/art.40699