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Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor‐conditioned macrophages

Macrophage plasticity is the ability of mononuclear phagocytes to change phenotype, function, and genetic reprogramming upon encounter of specific local stimuli. In the tumor microenvironment, Tumor‐Associated Macrophages (TAMs) acquire an immune‐suppressive and tumor‐promoting phenotype. With the a...

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Detalles Bibliográficos
Autores principales:	Maeda, Akihiro, Digifico, Elisabeth, Andon, Fernando T., Mantovani, Alberto, Allavena, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Immunomodulation and immune therapies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563448/ https://www.ncbi.nlm.nih.gov/pubmed/30779113 http://dx.doi.org/10.1002/eji.201847888

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