Cargando…
Genomic amplification of chromosome 7 in the Doxorubicin resistant K562 cell line
Acquisition of multi-drug resistance (MDR) is a major hindrance towards the successful treatment of cancers. Over expression of a range of ATP-dependent efflux pumps, particularly ABCB1 is a widely reported mechanism of cancer cell MDR. Approximately 30% acute myeloid leukemia (AML) patients demonst...
Autores principales: | Ibrahim, Sara.M, Karim, Sajjad, Abusamra, Heba, Pushparaj, Peter N, Khan, Jalaluddin A, Abuzenadah, Adel M, Gari, Mamdooh A, Bakhashab, Sherin, Ahmed, Farid, Al-Qahtani, Mohammed H |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563671/ https://www.ncbi.nlm.nih.gov/pubmed/31223218 http://dx.doi.org/10.6026/97320630014587 |
Ejemplares similares
-
WYE-354 restores Adriamycin sensitivity in multidrug-resistant acute myeloid leukemia cell lines
por: Ibrahim, Sara M., et al.
Publicado: (2019) -
Assessment of Radiation Induced Therapeutic Effect and Cytotoxicity in Cancer Patients Based on Transcriptomic Profiling
por: Karim, Sajjad, et al.
Publicado: (2016) -
Molecular docking of resveratrol with known protein structures as well as high-throughput meta-data analyses uncork the “French Paradox” and its potential “Druggable” targets in humans
por: Pushparaj, Peter Natesan, et al.
Publicado: (2014) -
Metformin improves the angiogenic potential of human CD34(+) cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction
por: Bakhashab, Sherin, et al.
Publicado: (2016) -
BioSearch: an in-house developed lab information management system for center of excellence in genomic medicine research
por: Karim, Sajjad, et al.
Publicado: (2014)