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Adenine‐Driven Structural Switch from a Two‐ to Three‐Quartet DNA G‐Quadruplex

A G‐rich sequence found in the regulatory region of the RANKL gene, which is associated with homeostasis of bone metabolism, folds into a two‐quartet basket‐type G‐quadruplex stabilized by A⋅G⋅A and G⋅G⋅G base‐triads. Perusal of local structural features together with G/A‐to‐T modifications uncovere...

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Detalles Bibliográficos
Autores principales:	Lenarčič Živković, Martina, Rozman, Jan, Plavec, Janez
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563693/ https://www.ncbi.nlm.nih.gov/pubmed/30222243 http://dx.doi.org/10.1002/anie.201809328

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