Cargando…

Kirenol Inhibits the Function and Inflammation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis in vitro and in vivo

Kirenol is a diterpenoid extracted from the Chinese herbal medicine Siegesbeckiae. Siegesbeckiae has been used to treat Rheumatoid arthritis (RA) in China for several centuries. RA is characterized by the proliferation of synoviocytes in inflamed synovia, as well as by their expression of inflammato...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Jing, Li, Qiang, Jin, Li, Qu, Yuan, Liang, Bi-Bo, Zhu, Xiao-Tong, Du, Hong-Yan, Jie, Li-Gang, Yu, Qing-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563775/ https://www.ncbi.nlm.nih.gov/pubmed/31244849 http://dx.doi.org/10.3389/fimmu.2019.01304

Ejemplares similares

Editorial: Immunomodulatory Functions of Fibroblast-like Synoviocytes in Joint Inflammation and Destruction during Rheumatoid Arthritis
por: Xu, Hanshi, et al.
Publicado: (2020)

Solute carrier nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes
por: Torres, Alyssa, et al.
Publicado: (2022)

SFRP5 Enhances Wnt5a Induced-Inflammation in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
por: Mahmoud, Dorra Elhaj, et al.
Publicado: (2021)

Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis
por: de Oliveira, Patricia Gnieslaw, et al.
Publicado: (2019)

Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes
por: Torres, Alyssa, et al.
Publicado: (2023)

Role and mechanism of fibroblast-activated protein-α expression on the surface of fibroblast-like synoviocytes in rheumatoid arthritis
por: Wang, Zihan, et al.
Publicado: (2023)

RHAMM induces progression of rheumatoid arthritis by enhancing the functions of fibroblast-like synoviocytes
por: Wu, Jing, et al.
Publicado: (2018)

PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
por: Li, Xiao-Feng, et al.
Publicado: (2021)

C-Reactive Protein Promotes the Activation of Fibroblast-Like Synoviocytes From Patients With Rheumatoid Arthritis
por: Fang, Zhengyu, et al.
Publicado: (2020)

SFRP1 Negatively Modulates Pyroptosis of Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis: A Review
por: Jiang, Ping, et al.
Publicado: (2022)

Photobiomodulation ameliorates inflammatory parameters in fibroblast-like synoviocytes and experimental animal models of rheumatoid arthritis
por: Ryu, Ji Hyeon, et al.
Publicado: (2023)

Quercetin suppresses inflammatory cytokine production in rheumatoid arthritis fibroblast-like synoviocytes
por: Sun, Hai-Tao, et al.
Publicado: (2021)

Smoothened Regulates Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Activation of Rho GTPase Signaling
por: Peng, Wei-xiang, et al.
Publicado: (2017)

The synovial fluid fibroblast-like synoviocyte: A long-neglected piece in the puzzle of rheumatoid arthritis pathogenesis
por: Mahmoud, Dorra Elhaj, et al.
Publicado: (2022)

Ontology and Function of Fibroblast-Like and Macrophage-Like Synoviocytes: How Do They Talk to Each Other and Can They Be Targeted for Rheumatoid Arthritis Therapy?
por: Tu, Jiajie, et al.
Publicado: (2018)

Long Non-Coding RNA GAPLINC Promotes Tumor-Like Biologic Behaviors of Fibroblast-Like Synoviocytes as MicroRNA Sponging in Rheumatoid Arthritis Patients
por: Mo, Bi Yao, et al.
Publicado: (2018)

Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis
por: Bustamante, Marta F., et al.
Publicado: (2017)

The Rheumatoid Arthritis Risk Gene AIRE Is Induced by Cytokines in Fibroblast-Like Synoviocytes and Augments the Pro-inflammatory Response
por: Bergström, Beatrice, et al.
Publicado: (2019)

Two Main Cellular Components in Rheumatoid Arthritis: Communication Between T Cells and Fibroblast-Like Synoviocytes in the Joint Synovium
por: Tu, Jiajie, et al.
Publicado: (2022)

Silibinin alleviates inflammation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes and has a therapeutic effect on arthritis in rats
por: Tong, W. W., et al.
Publicado: (2018)

Kruppel-Like Factor 4 Positively Regulates Autoimmune Arthritis in Mouse Models and Rheumatoid Arthritis in Patients via Modulating Cell Survival and Inflammation Factors of Fibroblast-Like Synoviocyte
por: Choi, Seungjin, et al.
Publicado: (2018)

Regulation of Immune Responses and Chronic Inflammation by Fibroblast-Like Synoviocytes
por: Yoshitomi, Hiroyuki
Publicado: (2019)

Anti-Inflammatory Effects of TRAF-Interacting Protein in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
por: Kong, Qing-Zhu, et al.
Publicado: (2016)

Sonic Hedgehog Signaling Pathway Mediates Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via MAPK/ERK Signaling Pathway
por: Liu, Fang, et al.
Publicado: (2018)

Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis
por: Li, Dan, et al.
Publicado: (2022)

YAP/TAZ: Key Players for Rheumatoid Arthritis Severity by Driving Fibroblast Like Synoviocytes Phenotype and Fibro-Inflammatory Response
por: Caire, Robin, et al.
Publicado: (2021)

Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis
por: Kaneko, Kayoko, et al.
Publicado: (2011)

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
por: Ai, Rizi, et al.
Publicado: (2018)

Oridonin suppresses autophagy and survival in rheumatoid arthritis fibroblast-like synoviocytes
por: He, Shou-Di, et al.
Publicado: (2020)

Role of protein arginine methyltransferase 5 in inflammation and migration of fibroblast‐like synoviocytes in rheumatoid arthritis
por: Chen, Dongying, et al.
Publicado: (2016)

Spontaneously Resolving Joint Inflammation Is Characterised by Metabolic Agility of Fibroblast-Like Synoviocytes
por: Falconer, Jane, et al.
Publicado: (2021)

Metabolomic Elucidation of the Effects of Curcumin on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
por: Ahn, Joong Kyong, et al.
Publicado: (2015)

Inhibition of BMP3 increases the inflammatory response of fibroblast-like synoviocytes in rheumatoid arthritis
por: Song, Biao, et al.
Publicado: (2020)

Functional role of PPAR-γ on the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis
por: Li, Xiao-Feng, et al.
Publicado: (2017)

Proinflammatory Effects of Ubiquitin-Specific Protease 5 (USP5) in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
por: Luo, Xiao-Bo, et al.
Publicado: (2020)

Long noncoding RNA expression profile in fibroblast-like synoviocytes from patients with rheumatoid arthritis
por: Zhang, Yu, et al.
Publicado: (2016)

The protective effect of kirenol in osteoarthritis: an in vitro and in vivo study
por: Hu, Wei, et al.
Publicado: (2022)

Insulin Exacerbates Inflammation in Fibroblast-Like Synoviocytes
por: Qiao, Li, et al.
Publicado: (2020)

Effects of inflammatory cytokine IL-27 on the activation of fibroblast-like synoviocytes in rheumatoid arthritis
por: Wong, Chun K, et al.
Publicado: (2010)

A two-herb formula inhibits hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes
por: Chen, Ying-Jie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vu3nrjfbtodql0f7bminebteq3