A Somatic Activating NRAS Variant Associated with Kaposiform Lymphangiomatosis

PURPOSE: Kaposiform lymphangiomatosis (KLA) is a rare, frequently aggressive, systemic disorder of the lymphatic vasculature, occurring primarily in children. Even with multimodal treatments, KLA has a poor prognosis and high mortality rate secondary to coagulopathy, effusions and systemic involveme...

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Detalles Bibliográficos
Autores principales: Barclay, Sarah F., Inman, Kyle W., Luks, Valerie L., McIntyre, John B., Al-Ibraheemi, Alyaa, Church, Alanna J., Perez-Atayde, Antonio R., Mangray, Shamlal, Jeng, Michael, Kreimer, Sara R., Walker, Lori, Fishman, Steven J., Alomari, Ahmad I., Chaudry, Gulraiz, Trenor, Cameron C., Adams, Denise, Kozakewich, Harry P.W., Kurek, Kyle C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565516/
https://www.ncbi.nlm.nih.gov/pubmed/30542204
http://dx.doi.org/10.1038/s41436-018-0390-0

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