Cargando…

Analysis of deletional hereditary persistence of fetal hemoglobin/δβ‐thalassemia and δ‐globin gene mutations in Southerwestern China

BACKGROUND: Deletional hereditary persistence of fetal hemoglobin (HPFH)/δβ‐thalassemia and δ‐thalassemia are rare inherited disorders which may complicate the diagnosis of β‐thalassemia. The aim of this study was to reveal the frequency of these two disorders in Southwestern China. METHODS: A total...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jie, Yang, Yang, Li, Peng, Yan, Yuanlong, Lv, Tao, Zhao, Tingting, Zeng, Xiaohong, Li, Dongmei, Zhou, Xiaoyan, Chen, Hong, Su, Jie, Yang, Tonghua, He, Jing, Zhu, Baosheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565566/ https://www.ncbi.nlm.nih.gov/pubmed/31044540 http://dx.doi.org/10.1002/mgg3.706

Ejemplares similares

The prevalence and molecular characterization of (δβ)(0)‐thalassemia and hereditary persistence of fetal hemoglobin in the Chinese Zhuang population
por: He, Sheng, et al.
Publicado: (2017)

Molecular epidemiology and hematologic characterization of δβ-thalassemia and hereditary persistence of fetal hemoglobin in 125,661 families of greater Guangzhou area, the metropolis of southern China
por: Jiang, Fan, et al.
Publicado: (2020)

Induction of Fetal Hemoglobin by Introducing Natural Hereditary Persistence of Fetal Hemoglobin Mutations in the γ-Globin Gene Promoters for Genome Editing Therapies for β-Thalassemia
por: Lu, Dian, et al.
Publicado: (2022)

HbS-Sicilian (δβ)(0)-Thalassemia: A Rare Variant of Sickle Cell
por: Onimoe, Grace, et al.
Publicado: (2017)

Gap-PCR Screening for Common Large Deletional Mutations of β-Globin Gene Cluster Revealed a Higher Prevalence of the Turkish Inversion/Deletion (δβ)0 Mutation in Antalya
por: Bilgen, Türker, et al.
Publicado: (2016)

An Aγ-globin G->A gene polymorphism associated with β(0)39 thalassemia globin gene and high fetal hemoglobin production
por: Breveglieri, Giulia, et al.
Publicado: (2017)

Correlation of BACH1 and Hemoglobin E/Beta-Thalassemia Globin Expression
por: Lee, Tze Yan, et al.
Publicado: (2016)

Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin
por: Doerfler, Phillip A., et al.
Publicado: (2021)

Hereditary persistence of fetal hemoglobin
por: Sharma, Dharmesh Chandra, et al.
Publicado: (2020)

Five novel globin gene mutations identified in five Chinese families by next‐generation sequencing
por: Zhang, Jie, et al.
Publicado: (2021)

First report of the spectrum of δ‐globin gene mutations among women of reproductive age in Fujian area—Discrimination of δ‐thalassemia, α‐thalassemia, and Iron Deficiency Anemia
por: Chen, Meihuan, et al.
Publicado: (2020)

Prevention of Transcriptional γ-globin Gene Silencing by Inducing The Hereditary Persistence of Fetal Hemoglobin Point Mutation Using Chimeraplast-Mediated Gene Targeting
por: Ranjbaran, Reza, et al.
Publicado: (2018)

3′HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression
por: Himadewi, Pamela, et al.
Publicado: (2021)

The Frequency and Importance of Common α-globin Gene Deletions Among β-Thalassemia Carriers in an Iranian Population
por: Moosavi, Azam, et al.
Publicado: (2017)

The Frequency and Importance of Common α-globin Gene Deletions Among β-Thalassemia Carriers in an Iranian Population
por: Moosavi, Azam, et al.
Publicado: (2018)

Immunostick Test for Detecting ζ-Globin Chains and Screening of the Southeast Asian α-Thalassemia 1 Deletion
por: Pata, Supansa, et al.
Publicado: (2019)

Alpha-Thalassemia in Southern Italy: Characterization of Five New Deletions Removing the Alpha-Globin Gene Cluster
por: Cardiero, Giovanna, et al.
Publicado: (2023)

Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β(0)39-Globin Gene Editing and Induction of Fetal Hemoglobin
por: Cosenza, Lucia Carmela, et al.
Publicado: (2022)

Induction of Fetal Hemoglobin In Vivo Mediated by a Synthetic γ-Globin Zinc Finger Activator
por: Costa, Flávia C., et al.
Publicado: (2012)

Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
por: Fong, Cristian, et al.
Publicado: (2020)

Evaluation of Signaling Pathways Involved in γ-Globin Gene Induction Using Fetal Hemoglobin Inducer Drugs
por: Rahim, Fakher, et al.
Publicado: (2013)

β-Globin chain abnormalities with coexisting α-thalassemia mutations
por: Guvenc, Birol, et al.
Publicado: (2012)

β-Thalassemia Intermedia: Interaction of α-Globin Gene Triplication With β-thalassemia Heterozygous in Spain
por: Ropero, Paloma, et al.
Publicado: (2022)

Impact of the detection of ζ-globin chains and hemoglobin Bart’s using immunochromatographic strip tests for α(0)-thalassemia (--(SEA)) differential diagnosis
por: Pata, Supansa, et al.
Publicado: (2019)

Blessing in disguise; a case of Hereditary Persistence of Fetal Hemoglobin
por: Shaukat, Irfan, et al.
Publicado: (2018)

GLOBIN UTILIZATION BY THE ANEMIC DOG TO FORM NEW HEMOGLOBIN
por: Robscheit-Robbins, F. S., et al.
Publicado: (1937)

Trienone analogs of curcuminoids induce fetal hemoglobin synthesis via demethylation at (G)γ-globin gene promoter
por: Nuamsee, Khanita, et al.
Publicado: (2021)

Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling
por: De Souza, Daniel C., et al.
Publicado: (2023)

Homozygous Deletion Alpha-Thalassemia and Hereditary Persistence of Fetal Hemoglobin, Two Genetic Factors Predictive the Reduction of Morbidity and Mortality During Pregnancy in Sickle Cell Patients. A Report from the Democratic Republic of Congo
por: Mikobi, Tite Minga, et al.
Publicado: (2019)

Molecular epidemiology, pathogenicity, and structural analysis of haemoglobin variants in the Yunnan province population of Southwestern China
por: Zhang, Jie, et al.
Publicado: (2019)

Construction and Analysis of a Long Non-Coding RNA (lncRNA)-Associated ceRNA Network in β-Thalassemia and Hereditary Persistence of Fetal Hemoglobin
por: Jia, Wenguang, et al.
Publicado: (2019)

Reciprocal regulation of γ-globin expression by exo-miRNAs: Relevance to γ-globin silencing in β-thalassemia major
por: Sun, Kuo-Ting, et al.
Publicado: (2017)

Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies
por: Venkatesan, Vigneshwaran, et al.
Publicado: (2023)

Beta Globin Frameworks in Thalassemia Major Patients from North Iran
por: Akhavan-Niaki, Haleh, et al.
Publicado: (2012)

Spectrum of Beta Globin Gene Mutations in Egyptian Children with β-Thalassemia
por: El-Shanshory, MR, et al.
Publicado: (2014)

DNA methylation patterns of β-globin cluster in β-thalassemia patients
por: Bao, Xiuqin, et al.
Publicado: (2020)

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression
por: Antoniou, Panagiotis, et al.
Publicado: (2022)

Pharmacological Induction of Fetal Hemoglobin in β-Thalassemia and Sickle Cell Disease: An Updated Perspective
por: Bou-Fakhredin, Rayan, et al.
Publicado: (2022)

Case Report: The third-generation sequencing confirmed a novel 7.2 Kb deletion at β-globin gene in a patient with rare β-thalassemia
por: Zhong, Guoxing, et al.
Publicado: (2022)

Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia
por: Nualkaew, Tiwaporn, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_07u6o1ng1keuuu0itiqfi6i929