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Modeling Motor Neuron Resilience in ALS Using Stem Cells
Oculomotor neurons, which regulate eye movement, are resilient to degeneration in the lethal motor neuron disease amyotrophic lateral sclerosis (ALS). It would be highly advantageous if motor neuron resilience could be modeled in vitro. Toward this goal, we generated a high proportion of oculomotor...
Autores principales: | Allodi, Ilary, Nijssen, Jik, Benitez, Julio Aguila, Schweingruber, Christoph, Fuchs, Andrea, Bonvicini, Gillian, Cao, Ming, Kiehn, Ole, Hedlund, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565614/ https://www.ncbi.nlm.nih.gov/pubmed/31080111 http://dx.doi.org/10.1016/j.stemcr.2019.04.009 |
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