Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme

Ribonuclease P (RNase P) is an essential ribozyme responsible for tRNA 5′ maturation. Here we report the cryo-EM structures of Methanocaldococcus jannaschii (Mja) RNase P holoenzyme alone and in complex with a tRNA substrate at resolutions of 4.6 Å and 4.3 Å, respectively. The structures reveal that...

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Detalles Bibliográficos
Autores principales: Wan, Futang, Wang, Qianmin, Tan, Jing, Tan, Ming, Chen, Juan, Shi, Shaohua, Lan, Pengfei, Wu, Jian, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565675/
https://www.ncbi.nlm.nih.gov/pubmed/31197137
http://dx.doi.org/10.1038/s41467-019-10496-3

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