Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) represents one of the most common heritable heart diseases. However, the signalling pathways and regulatory networks underlying the pathogenesis of HCM remain largely unknown. Here, we present a strand-specific RNA-seq dataset for both coding and lncRNA profiling in...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xuanyu, Ma, Yi, Yin, Kunlun, Li, Wenke, Chen, Wen, Zhang, Yujing, Zhu, Changsheng, Li, Tianjiao, Han, Bianmei, Liu, Xuewen, Wang, Shuiyun, Zhou, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565738/
https://www.ncbi.nlm.nih.gov/pubmed/31197155
http://dx.doi.org/10.1038/s41597-019-0094-6
Descripción
Sumario:Hypertrophic cardiomyopathy (HCM) represents one of the most common heritable heart diseases. However, the signalling pathways and regulatory networks underlying the pathogenesis of HCM remain largely unknown. Here, we present a strand-specific RNA-seq dataset for both coding and lncRNA profiling in myocardial tissues from 28 HCM patients and 9 healthy donors. This dataset constitutes a valuable resource for the community to examine the dysregulated coding and lncRNA genes in HCM versus normal conditions.

Ejemplares similares