Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) represents one of the most common heritable heart diseases. However, the signalling pathways and regulatory networks underlying the pathogenesis of HCM remain largely unknown. Here, we present a strand-specific RNA-seq dataset for both coding and lncRNA profiling in...

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Autores principales: Liu, Xuanyu, Ma, Yi, Yin, Kunlun, Li, Wenke, Chen, Wen, Zhang, Yujing, Zhu, Changsheng, Li, Tianjiao, Han, Bianmei, Liu, Xuewen, Wang, Shuiyun, Zhou, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565738/
https://www.ncbi.nlm.nih.gov/pubmed/31197155
http://dx.doi.org/10.1038/s41597-019-0094-6
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author Liu, Xuanyu
Ma, Yi
Yin, Kunlun
Li, Wenke
Chen, Wen
Zhang, Yujing
Zhu, Changsheng
Li, Tianjiao
Han, Bianmei
Liu, Xuewen
Wang, Shuiyun
Zhou, Zhou
author_facet Liu, Xuanyu
Ma, Yi
Yin, Kunlun
Li, Wenke
Chen, Wen
Zhang, Yujing
Zhu, Changsheng
Li, Tianjiao
Han, Bianmei
Liu, Xuewen
Wang, Shuiyun
Zhou, Zhou
author_sort Liu, Xuanyu
collection PubMed
description Hypertrophic cardiomyopathy (HCM) represents one of the most common heritable heart diseases. However, the signalling pathways and regulatory networks underlying the pathogenesis of HCM remain largely unknown. Here, we present a strand-specific RNA-seq dataset for both coding and lncRNA profiling in myocardial tissues from 28 HCM patients and 9 healthy donors. This dataset constitutes a valuable resource for the community to examine the dysregulated coding and lncRNA genes in HCM versus normal conditions.
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spelling pubmed-65657382019-06-21 Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy Liu, Xuanyu Ma, Yi Yin, Kunlun Li, Wenke Chen, Wen Zhang, Yujing Zhu, Changsheng Li, Tianjiao Han, Bianmei Liu, Xuewen Wang, Shuiyun Zhou, Zhou Sci Data Data Descriptor Hypertrophic cardiomyopathy (HCM) represents one of the most common heritable heart diseases. However, the signalling pathways and regulatory networks underlying the pathogenesis of HCM remain largely unknown. Here, we present a strand-specific RNA-seq dataset for both coding and lncRNA profiling in myocardial tissues from 28 HCM patients and 9 healthy donors. This dataset constitutes a valuable resource for the community to examine the dysregulated coding and lncRNA genes in HCM versus normal conditions. Nature Publishing Group UK 2019-06-13 /pmc/articles/PMC6565738/ /pubmed/31197155 http://dx.doi.org/10.1038/s41597-019-0094-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files associated with this article.
spellingShingle Data Descriptor
Liu, Xuanyu
Ma, Yi
Yin, Kunlun
Li, Wenke
Chen, Wen
Zhang, Yujing
Zhu, Changsheng
Li, Tianjiao
Han, Bianmei
Liu, Xuewen
Wang, Shuiyun
Zhou, Zhou
Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy
title Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy
title_full Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy
title_fullStr Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy
title_full_unstemmed Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy
title_short Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy
title_sort long non-coding and coding rna profiling using strand-specific rna-seq in human hypertrophic cardiomyopathy
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565738/
https://www.ncbi.nlm.nih.gov/pubmed/31197155
http://dx.doi.org/10.1038/s41597-019-0094-6
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