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The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells
Insulin secretion from pancreatic beta-cells is dependent on zinc ions as essential components of insulin crystals, zinc transporters are thus involved in the insulin secretory process. Zip14 (SLC39a14) is a zinc importing protein that has an important role in glucose homeostasis. Zip14 knockout mic...
Autores principales: | Maxel, Trine, Smidt, Kamille, Petersen, Charlotte C., Honoré, Bent, Christensen, Anne K., Jeppesen, Per B., Brock, Birgitte, Rungby, Jørgen, Palmfeldt, Johan, Larsen, Agnete |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565745/ https://www.ncbi.nlm.nih.gov/pubmed/31197210 http://dx.doi.org/10.1038/s41598-019-44954-1 |
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