Cardiac interstitial tetraploid cells can escape replicative senescence in rodents but not large mammals

Cardiomyocyte ploidy has been described but remains obscure in cardiac interstitial cells. Ploidy of c-kit+ cardiac interstitial cells was assessed using confocal, karyotypic, and flow cytometric technique. Notable differences were found between rodent (rat, mouse) c-kit+ cardiac interstitial cells...

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Detalles Bibliográficos
Autores principales: Broughton, Kathleen M., Khieu, Tiffany, Nguyen, Nicky, Rosa, Michael, Mohsin, Sadia, Quijada, Pearl, Wang, Bingyan J., Echeagaray, Oscar H., Kubli, Dieter A., Kim, Taeyong, Firouzi, Fareheh, Monsanto, Megan M., Gude, Natalie A., Adamson, Robert M., Dembitsky, Walter P., Davis, Michael E., Sussman, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565746/
https://www.ncbi.nlm.nih.gov/pubmed/31231694
http://dx.doi.org/10.1038/s42003-019-0453-z

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