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Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection

Chagas disease (ChD) is one of the most neglected tropical diseases, with cardiomyopathy being the main cause of death in Trypanosoma cruzi-infected patients. As the parasite actively replicates in cardiomyocytes (CMs), the heart remains a key target organ in the pathogenesis of ChD. Here we modeled...

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Detalles Bibliográficos
Autores principales: Bozzi, Adriana, Sayed, Nazish, Matsa, Elena, Sass, Gabriele, Neofytou, Evgenios, Clemons, Karl V., Correa-Oliveira, Rodrigo, Stevens, David A., Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565757/
https://www.ncbi.nlm.nih.gov/pubmed/31105048
http://dx.doi.org/10.1016/j.stemcr.2019.04.017