Losmapimod Protected Epileptic Rats From Hippocampal Neuron Damage Through Inhibition of the MAPK Pathway

Objective: This research aimed to validate the therapeutic effect of losmapimod and explore the underlying mechanism in its treatment of epilepsy. Methods: A rat model of epilepsy was constructed with an injection of pilocarpine. Microarray analysis was performed to screen aberrantly expressed mRNAs...

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Detalles Bibliográficos
Autores principales: Li, Min, Cui, Lexiang, Feng, Xuemin, Wang, Chao, Zhang, Yinmeng, Wang, Lijie, Ding, Ying, Zhao, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565798/
https://www.ncbi.nlm.nih.gov/pubmed/31231220
http://dx.doi.org/10.3389/fphar.2019.00625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565798/
https://www.ncbi.nlm.nih.gov/pubmed/31231220
http://dx.doi.org/10.3389/fphar.2019.00625

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