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Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner

Fibroblast Growth Factor Homologous Factors (FHF) constitute a subfamily of FGF proteins with four prototypes (FHF1-4; also known as FGF11-14). FHF proteins have been shown to bind directly to the membrane-proximal segment of the C-terminus in voltage-gated sodium channels (Nav), and regulate curren...

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Detalles Bibliográficos
Autores principales: Effraim, Philip R., Huang, Jianying, Lampert, Angelika, Stamboulian, Severine, Zhao, Peng, Black, Joel A., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565799/
https://www.ncbi.nlm.nih.gov/pubmed/31223136
http://dx.doi.org/10.1016/j.ynpai.2019.100029

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