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The purinergic receptor antagonist oxidized adenosine triphosphate suppresses immune-mediated corneal allograft rejection
Adenosine triphosphate (ATP) is released into the extracellular environment during transplantation, and acts via purinergic receptors to amplify the alloimmune response. Here, using a well-established murine model of allogeneic corneal transplantation, we investigated the immunomodulatory mechanisms...
Autores principales: | Foulsham, William, Mittal, Sharad K., Nakao, Takeshi, Coco, Giulia, Taketani, Yukako, Chauhan, Sunil K., Dana, Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565802/ https://www.ncbi.nlm.nih.gov/pubmed/31197223 http://dx.doi.org/10.1038/s41598-019-44973-y |
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