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Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion

Tilapia skin has non-infectious microbiota, high amounts of type I collagen, and similar morphological structure to human skin, so it has been suggested as a potential xenograft for the management of burn wounds. A 23-year-old male patient, with no comorbidities, arrived at our burn treatment center...

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Detalles Bibliográficos
Autores principales: Lima-Junior, Edmar Maciel, de Moraes Filho, Manoel Odorico, Costa, Bruno Almeida, Fechine, Francisco Vagnaldo, de Moraes, Maria Elisabete Amaral, Silva-Junior, Francisco Raimundo, Soares, Maria Flaviane Araújo do Nascimento, Rocha, Marina Becker Sales, Leontsinis, Cybele Maria Philopimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565829/
https://www.ncbi.nlm.nih.gov/pubmed/31214319
http://dx.doi.org/10.1093/jscr/rjz181
Descripción
Sumario:Tilapia skin has non-infectious microbiota, high amounts of type I collagen, and similar morphological structure to human skin, so it has been suggested as a potential xenograft for the management of burn wounds. A 23-year-old male patient, with no comorbidities, arrived at our burn treatment center after a thermal injury caused by contact with flames from a gunpowder explosion. Superficial partial thickness burns were present in his right upper limb and deep partial thickness burns were present in his left upper limb. Tilapia skin was applied to the lesions, leading to complete reepithelialization within 12 and 17 days of treatment, respectively. No dressing changes were needed and no side effects were observed. Tilapia skin carries the promise of an innovative, easy-to-apply and highly available product that can become the first nationally studied animal skin registered by the National Sanitary Surveillance Agency for use in the treatment of burns.