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Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion

Tilapia skin has non-infectious microbiota, high amounts of type I collagen, and similar morphological structure to human skin, so it has been suggested as a potential xenograft for the management of burn wounds. A 23-year-old male patient, with no comorbidities, arrived at our burn treatment center...

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Autores principales: Lima-Junior, Edmar Maciel, de Moraes Filho, Manoel Odorico, Costa, Bruno Almeida, Fechine, Francisco Vagnaldo, de Moraes, Maria Elisabete Amaral, Silva-Junior, Francisco Raimundo, Soares, Maria Flaviane Araújo do Nascimento, Rocha, Marina Becker Sales, Leontsinis, Cybele Maria Philopimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565829/
https://www.ncbi.nlm.nih.gov/pubmed/31214319
http://dx.doi.org/10.1093/jscr/rjz181
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author Lima-Junior, Edmar Maciel
de Moraes Filho, Manoel Odorico
Costa, Bruno Almeida
Fechine, Francisco Vagnaldo
de Moraes, Maria Elisabete Amaral
Silva-Junior, Francisco Raimundo
Soares, Maria Flaviane Araújo do Nascimento
Rocha, Marina Becker Sales
Leontsinis, Cybele Maria Philopimin
author_facet Lima-Junior, Edmar Maciel
de Moraes Filho, Manoel Odorico
Costa, Bruno Almeida
Fechine, Francisco Vagnaldo
de Moraes, Maria Elisabete Amaral
Silva-Junior, Francisco Raimundo
Soares, Maria Flaviane Araújo do Nascimento
Rocha, Marina Becker Sales
Leontsinis, Cybele Maria Philopimin
author_sort Lima-Junior, Edmar Maciel
collection PubMed
description Tilapia skin has non-infectious microbiota, high amounts of type I collagen, and similar morphological structure to human skin, so it has been suggested as a potential xenograft for the management of burn wounds. A 23-year-old male patient, with no comorbidities, arrived at our burn treatment center after a thermal injury caused by contact with flames from a gunpowder explosion. Superficial partial thickness burns were present in his right upper limb and deep partial thickness burns were present in his left upper limb. Tilapia skin was applied to the lesions, leading to complete reepithelialization within 12 and 17 days of treatment, respectively. No dressing changes were needed and no side effects were observed. Tilapia skin carries the promise of an innovative, easy-to-apply and highly available product that can become the first nationally studied animal skin registered by the National Sanitary Surveillance Agency for use in the treatment of burns.
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spelling pubmed-65658292019-06-18 Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion Lima-Junior, Edmar Maciel de Moraes Filho, Manoel Odorico Costa, Bruno Almeida Fechine, Francisco Vagnaldo de Moraes, Maria Elisabete Amaral Silva-Junior, Francisco Raimundo Soares, Maria Flaviane Araújo do Nascimento Rocha, Marina Becker Sales Leontsinis, Cybele Maria Philopimin J Surg Case Rep Case Report Tilapia skin has non-infectious microbiota, high amounts of type I collagen, and similar morphological structure to human skin, so it has been suggested as a potential xenograft for the management of burn wounds. A 23-year-old male patient, with no comorbidities, arrived at our burn treatment center after a thermal injury caused by contact with flames from a gunpowder explosion. Superficial partial thickness burns were present in his right upper limb and deep partial thickness burns were present in his left upper limb. Tilapia skin was applied to the lesions, leading to complete reepithelialization within 12 and 17 days of treatment, respectively. No dressing changes were needed and no side effects were observed. Tilapia skin carries the promise of an innovative, easy-to-apply and highly available product that can become the first nationally studied animal skin registered by the National Sanitary Surveillance Agency for use in the treatment of burns. Oxford University Press 2019-06-14 /pmc/articles/PMC6565829/ /pubmed/31214319 http://dx.doi.org/10.1093/jscr/rjz181 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2019. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Lima-Junior, Edmar Maciel
de Moraes Filho, Manoel Odorico
Costa, Bruno Almeida
Fechine, Francisco Vagnaldo
de Moraes, Maria Elisabete Amaral
Silva-Junior, Francisco Raimundo
Soares, Maria Flaviane Araújo do Nascimento
Rocha, Marina Becker Sales
Leontsinis, Cybele Maria Philopimin
Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion
title Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion
title_full Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion
title_fullStr Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion
title_full_unstemmed Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion
title_short Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion
title_sort innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565829/
https://www.ncbi.nlm.nih.gov/pubmed/31214319
http://dx.doi.org/10.1093/jscr/rjz181
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