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A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs
Human induced pluripotent stem cell (iPSC)-derived developmental lineages are key tools for in vitro mechanistic interrogations, drug discovery, and disease modeling. iPSCs have previously been differentiated to endothelial cells with blood-brain barrier (BBB) properties, as defined by high transend...
Autores principales: | Neal, Emma H., Marinelli, Nicholas A., Shi, Yajuan, McClatchey, P. Mason, Balotin, Kylie M., Gullett, Dalton R., Hagerla, Kameron A., Bowman, Aaron B., Ess, Kevin C., Wikswo, John P., Lippmann, Ethan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565873/ https://www.ncbi.nlm.nih.gov/pubmed/31189096 http://dx.doi.org/10.1016/j.stemcr.2019.05.008 |
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