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A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs

Human induced pluripotent stem cell (iPSC)-derived developmental lineages are key tools for in vitro mechanistic interrogations, drug discovery, and disease modeling. iPSCs have previously been differentiated to endothelial cells with blood-brain barrier (BBB) properties, as defined by high transend...

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Detalles Bibliográficos
Autores principales: Neal, Emma H., Marinelli, Nicholas A., Shi, Yajuan, McClatchey, P. Mason, Balotin, Kylie M., Gullett, Dalton R., Hagerla, Kameron A., Bowman, Aaron B., Ess, Kevin C., Wikswo, John P., Lippmann, Ethan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565873/
https://www.ncbi.nlm.nih.gov/pubmed/31189096
http://dx.doi.org/10.1016/j.stemcr.2019.05.008

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