Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands

Fatty Acid Amide Hydrolase (FAAH) is one of the main enzymes responsible for endocannabinoid metabolism. Inhibition of FAAH increases endogenous levels of fatty acid ethanolamides such as anandamide (AEA) and thus consitutes an indirect strategy that can be used to modulate endocannabinoid tone. In...

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Detalles Bibliográficos
Autores principales: Lorca, Marcos, Valdes, Yudisladys, Chung, Hery, Romero-Parra, Javier, Pessoa-Mahana, C. David, Mella, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566251/
https://www.ncbi.nlm.nih.gov/pubmed/31117309
http://dx.doi.org/10.3390/ijms20102510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566251/
https://www.ncbi.nlm.nih.gov/pubmed/31117309
http://dx.doi.org/10.3390/ijms20102510

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