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Engineering of Nanobodies Recognizing the Human Chemokine Receptor CCR7

The chemokine receptor CCR7 plays a pivotal role in health and disease. In particular, CCR7 controls homing of antigen-bearing dendritic cells and T cells to lymph nodes, where adaptive immune responses are initiated. However, CCR7 also guides T cells to inflamed synovium and thereby contributes to...

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Detalles Bibliográficos
Autores principales:	Jakobs, Barbara D., Spannagel, Lisa, Purvanov, Vladimir, Uetz-von Allmen, Edith, Matti, Christoph, Legler, Daniel F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566259/ https://www.ncbi.nlm.nih.gov/pubmed/31137829 http://dx.doi.org/10.3390/ijms20102597

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