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The Role of Heme Oxygenase 1 in the Protective Effect of Caloric Restriction against Diabetic Cardiomyopathy

Type 2 diabetes mellitus (DM2) leads to cardiomyopathy characterized by cardiomyocyte hypertrophy, followed by mitochondrial dysfunction and interstitial fibrosis, all of which are exacerbated by angiotensin II (AT). SIRT1 and its transcriptional coactivator target PGC-1α (peroxisome proliferator-ac...

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Detalles Bibliográficos
Autores principales: Waldman, Maayan, Nudelman, Vadim, Shainberg, Asher, Zemel, Romy, Kornwoski, Ran, Aravot, Dan, Peterson, Stephen J., Arad, Michael, Hochhauser, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566501/
https://www.ncbi.nlm.nih.gov/pubmed/31100876
http://dx.doi.org/10.3390/ijms20102427