Cargando…

Transfer of the Experimental Autoimmune Glaucoma Model from Rats to Mice—New Options to Study Glaucoma Disease

Studies have suggested an involvement of the immune system in glaucoma. Hence, a rat experimental autoimmune glaucoma model (EAG) was developed to investigate the role of the immune response. Here, we transferred this model into mice. Either 0.8 mg/mL of the optic nerve antigen homogenate (ONA; ONA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reinehr, Sabrina, Reinhard, Jacqueline, Wiemann, Susanne, Hesse, Karoline, Voss, Christina, Gandej, Marcel, Dick, H. Burkhard, Faissner, Andreas, Joachim, Stephanie C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566658/ https://www.ncbi.nlm.nih.gov/pubmed/31137749 http://dx.doi.org/10.3390/ijms20102563

Ejemplares similares

Simultaneous Complement Response via Lectin Pathway in Retina and Optic Nerve in an Experimental Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2016)

S100B immunization triggers NFκB and complement activation in an autoimmune glaucoma model
por: Reinehr, Sabrina, et al.
Publicado: (2018)

Early remodelling of the extracellular matrix proteins tenascin‐C and phosphacan in retina and optic nerve of an experimental autoimmune glaucoma model
por: Reinehr, Sabrina, et al.
Publicado: (2016)

Loss of the Extracellular Matrix Molecule Tenascin-C Leads to Absence of Reactive Gliosis and Promotes Anti-inflammatory Cytokine Expression in an Autoimmune Glaucoma Mouse Model
por: Wiemann, Susanne, et al.
Publicado: (2020)

Extracellular Matrix Remodeling in the Retina and Optic Nerve of a Novel Glaucoma Mouse Model
por: Reinhard, Jacqueline, et al.
Publicado: (2021)

Preservation of optic nerve structure by complement inhibition in experimental glaucoma
por: Gassel, Caroline J., et al.
Publicado: (2020)

Correction to: Preservation of optic nerve structure by complement inhibition in experimental glaucoma
por: Gassel, Caroline J., et al.
Publicado: (2021)

Proteomic Analysis of Retinal Tissue in an S100B Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2021)

Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2019)

Loss of retinal ganglion cells in a new genetic mouse model for primary open‐angle glaucoma
por: Reinehr, Sabrina, et al.
Publicado: (2019)

Heat Shock Protein Upregulation Supplemental to Complex mRNA Alterations in Autoimmune Glaucoma
por: Reinehr, Sabrina, et al.
Publicado: (2022)

Immune response against ocular tissues after immunization with optic nerve antigens in a model of autoimmune glaucoma
por: Joachim, Stephanie C., et al.
Publicado: (2013)

Synapse and Receptor Alterations in Two Different S100B-Induced Glaucoma-Like Models
por: Benning, Lara, et al.
Publicado: (2020)

Role of Heat Shock Proteins in Glaucoma
por: Tsai, Teresa, et al.
Publicado: (2019)

Immune Mediated Degeneration and Possible Protection in Glaucoma
por: Tsai, Teresa, et al.
Publicado: (2019)

Laquinimod protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model
por: Wilmes, Anna T., et al.
Publicado: (2018)

Ischemic injury leads to extracellular matrix alterations in retina and optic nerve
por: Reinhard, Jacqueline, et al.
Publicado: (2017)

The pathology behind glaucoma: what we already know using omics technologies
por: May, Caroline, et al.
Publicado: (2023)

Optic Nerve Degeneration after Retinal Ischemia/Reperfusion in a Rodent Model
por: Renner, Marina, et al.
Publicado: (2017)

Is glaucoma an autoimmune disease?
por: Wakefield, Denis, et al.
Publicado: (2020)

Protective effects on the retina after ranibizumab treatment in an ischemia model
por: Joachim, Stephanie C., et al.
Publicado: (2017)

T Cell-Mediated Autoimmunity in Glaucoma Neurodegeneration
por: Wang, Lixiang, et al.
Publicado: (2021)

Current Surgical Options for the Management of Pediatric Glaucoma
por: Morales, Jose, et al.
Publicado: (2013)

24-h Efficacy of Glaucoma Treatment Options
por: Konstas, Anastasios G. P., et al.
Publicado: (2016)

Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options
por: Yüksel, Nurşen, et al.
Publicado: (2023)

An emerging treatment option for glaucoma: Rho kinase inhibitors
por: Wang, Sean K, et al.
Publicado: (2014)

Noninvasive Glaucoma Procedures: Current Options and Future Innovations
por: Abdelrahman, Ahmed M.
Publicado: (2015)

Erratum to: 24-h Efficacy of Glaucoma Treatment Options
por: Konstas, Anastasios G. P., et al.
Publicado: (2016)

Apoptotic retinal ganglion cell loss is accompanied by complement and cytokine response in the βB1-CTGF primary open-angle glaucoma mouse model
por: Mueller-Buehl, Ana Maria, et al.
Publicado: (2022)

Intravitreal S100B Injection Leads to Progressive Glaucoma Like Damage in Retina and Optic Nerve
por: Kuehn, Sandra, et al.
Publicado: (2018)

Glaucoma and the Glaucoma Theories
por: Paterson, J. V.
Publicado: (1904)

Progressive Retinal and Optic Nerve Damage in a Mouse Model of Spontaneous Opticospinal Encephalomyelitis
por: Petrikowski, Laura, et al.
Publicado: (2022)

Cyclodestructive Procedures in Glaucoma: A Review of Current and Emerging Options
por: Dastiridou, Anna I., et al.
Publicado: (2018)

Anti-glaucoma potential of hesperidin in experimental glaucoma induced rats
por: Lu, Baiyang, et al.
Publicado: (2020)

Anti-glaucoma potential of Heliotropium indicum Linn in experimentally-induced glaucoma
por: Kyei, Samuel, et al.
Publicado: (2015)

HSP27 induced glaucomatous damage in mice of young and advanced age
por: Erb, Clivia, et al.
Publicado: (2023)

The Role of Neuroinflammation in Glaucoma: An Update on Molecular Mechanisms and New Therapeutic Options
por: Rolle, Teresa, et al.
Publicado: (2021)

New solutions for old challenges in glaucoma treatment: is taurine an option to consider?
por: Iezhitsa, Igor, et al.
Publicado: (2020)

Miniaturization in Glaucoma Monitoring and Treatment: A Review of New Technologies That Require a Minimal Surgical Approach
por: Dick, H. Burkhard, et al.
Publicado: (2019)

Glaucoma :
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cgruithqrintv7muh9qiv479bi