Melanocortin-4 Receptor and Lipocalin 2 Gene Variants in Spanish Children with Abdominal Obesity: Effects on BMI-SDS after a Lifestyle Intervention

Mutations leading to a reduced function of the melanocortin-4 receptor (MC4R) exert a major gene effect on extreme obesity. Recently it was shown that the bone derived hormone lipocalin 2 (LCN2) binds to the MC4R and activates a MC4R dependent anorexigenic pathway. We identified mutations in both ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Morell-Azanza, Lydia, Ojeda-Rodríguez, Ana, Giuranna, Johanna, Azcona-SanJulián, Mª Cristina, Hebebrand, Johannes, Marti, Amelia, Hinney, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566731/
https://www.ncbi.nlm.nih.gov/pubmed/31035493
http://dx.doi.org/10.3390/nu11050960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566731/
https://www.ncbi.nlm.nih.gov/pubmed/31035493
http://dx.doi.org/10.3390/nu11050960

Ejemplares similares