Cargando…

Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring

The synthesis by pulsed laser ablation and the characterization of both the surface nanostructure and the optical properties of noble metal nanoparticle-based substrates used in Surface Enhanced Raman Spectroscopy are discussed with reference to application in the detection of anti-epileptic drugs....

Descripción completa

Detalles Bibliográficos
Autores principales: Tommasini, Matteo, Zanchi, Chiara, Lucotti, Andrea, Bombelli, Alessandro, Villa, Nicolò S., Casazza, Marina, Ciusani, Emilio, de Grazia, Ugo, Santoro, Marco, Fazio, Enza, Neri, Fortunato, Trusso, Sebastiano, Ossi, Paolo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566808/
https://www.ncbi.nlm.nih.gov/pubmed/31052433
http://dx.doi.org/10.3390/nano9050677
_version_ 1783426933895200768
author Tommasini, Matteo
Zanchi, Chiara
Lucotti, Andrea
Bombelli, Alessandro
Villa, Nicolò S.
Casazza, Marina
Ciusani, Emilio
de Grazia, Ugo
Santoro, Marco
Fazio, Enza
Neri, Fortunato
Trusso, Sebastiano
Ossi, Paolo M.
author_facet Tommasini, Matteo
Zanchi, Chiara
Lucotti, Andrea
Bombelli, Alessandro
Villa, Nicolò S.
Casazza, Marina
Ciusani, Emilio
de Grazia, Ugo
Santoro, Marco
Fazio, Enza
Neri, Fortunato
Trusso, Sebastiano
Ossi, Paolo M.
author_sort Tommasini, Matteo
collection PubMed
description The synthesis by pulsed laser ablation and the characterization of both the surface nanostructure and the optical properties of noble metal nanoparticle-based substrates used in Surface Enhanced Raman Spectroscopy are discussed with reference to application in the detection of anti-epileptic drugs. Results on two representative drugs, namely Carbamazepine and Perampanel, are critically addressed.
format Online
Article
Text
id pubmed-6566808
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-65668082019-06-17 Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring Tommasini, Matteo Zanchi, Chiara Lucotti, Andrea Bombelli, Alessandro Villa, Nicolò S. Casazza, Marina Ciusani, Emilio de Grazia, Ugo Santoro, Marco Fazio, Enza Neri, Fortunato Trusso, Sebastiano Ossi, Paolo M. Nanomaterials (Basel) Article The synthesis by pulsed laser ablation and the characterization of both the surface nanostructure and the optical properties of noble metal nanoparticle-based substrates used in Surface Enhanced Raman Spectroscopy are discussed with reference to application in the detection of anti-epileptic drugs. Results on two representative drugs, namely Carbamazepine and Perampanel, are critically addressed. MDPI 2019-05-01 /pmc/articles/PMC6566808/ /pubmed/31052433 http://dx.doi.org/10.3390/nano9050677 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tommasini, Matteo
Zanchi, Chiara
Lucotti, Andrea
Bombelli, Alessandro
Villa, Nicolò S.
Casazza, Marina
Ciusani, Emilio
de Grazia, Ugo
Santoro, Marco
Fazio, Enza
Neri, Fortunato
Trusso, Sebastiano
Ossi, Paolo M.
Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring
title Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring
title_full Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring
title_fullStr Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring
title_full_unstemmed Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring
title_short Laser-Synthesized SERS Substrates as Sensors toward Therapeutic Drug Monitoring
title_sort laser-synthesized sers substrates as sensors toward therapeutic drug monitoring
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566808/
https://www.ncbi.nlm.nih.gov/pubmed/31052433
http://dx.doi.org/10.3390/nano9050677
work_keys_str_mv AT tommasinimatteo lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT zanchichiara lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT lucottiandrea lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT bombellialessandro lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT villanicolos lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT casazzamarina lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT ciusaniemilio lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT degraziaugo lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT santoromarco lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT fazioenza lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT nerifortunato lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT trussosebastiano lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring
AT ossipaolom lasersynthesizedserssubstratesassensorstowardtherapeuticdrugmonitoring