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Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes

Few evaluations of interventions to delay or prevent type 2 diabetes mellitus (T2DM) in Saudi Arabia (SA) have been undertaken. The present study evaluates the impact of a 6-month intensive lifestyle modification intervention delivered in primary care. Females from SA with prediabetes, aged 18–55 ye...

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Autores principales: Al-Hamdan, Rasha, Avery, Amanda, Salter, Andrew, Al-Disi, Dara, Al-Daghri, Nasser M., McCullough, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566809/
https://www.ncbi.nlm.nih.gov/pubmed/31109110
http://dx.doi.org/10.3390/nu11051113
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author Al-Hamdan, Rasha
Avery, Amanda
Salter, Andrew
Al-Disi, Dara
Al-Daghri, Nasser M.
McCullough, Fiona
author_facet Al-Hamdan, Rasha
Avery, Amanda
Salter, Andrew
Al-Disi, Dara
Al-Daghri, Nasser M.
McCullough, Fiona
author_sort Al-Hamdan, Rasha
collection PubMed
description Few evaluations of interventions to delay or prevent type 2 diabetes mellitus (T2DM) in Saudi Arabia (SA) have been undertaken. The present study evaluates the impact of a 6-month intensive lifestyle modification intervention delivered in primary care. Females from SA with prediabetes, aged 18–55 years, were recruited with 190 participants eligible following screening and randomly allocated to receive a 3-month one-on-one, intensive lifestyle modification (intervention group (IG) n = 95) or standard guidance (control group (CG) n = 95). Participants completed questionnaires including demographic, dietary and physical activity data. Blood samples were collected at baseline, 3 and 6 months. A total of 123 (74 IG (age 40.6 ± 9.8 years; body mass index (BMI) 31.2 ± 7.0 kg/m(2)) and 49 CG (age 40.6 ± 12.7 years; BMI 32.3 ± 5.4 kg/m(2))) participants completed the study. After 6 months, haemoglobin A1c (HbA1c; primary endpoint) significantly improved in the IG than CG completers in between-group comparisons (p < 0.001). Comparison between groups showed significant improvements in overall energy intake, total and high density lipoprotein (HDL)-cholesterol in favour of IG (p-values < 0.001, 0.04 and <0.001, respectively). BMI and weight change were not clinically significant in between group comparisons. A 6-month, intense one-on-one intervention in lifestyle modification significantly improves glycaemic and cardio metabolic profile of females living in SA with pre-diabetes delivered in a primary care setting. Longer duration studies, using the same intervention, may determine whether a meaningful weight loss secondary to improved diet can be achieved.
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spelling pubmed-65668092019-06-17 Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes Al-Hamdan, Rasha Avery, Amanda Salter, Andrew Al-Disi, Dara Al-Daghri, Nasser M. McCullough, Fiona Nutrients Article Few evaluations of interventions to delay or prevent type 2 diabetes mellitus (T2DM) in Saudi Arabia (SA) have been undertaken. The present study evaluates the impact of a 6-month intensive lifestyle modification intervention delivered in primary care. Females from SA with prediabetes, aged 18–55 years, were recruited with 190 participants eligible following screening and randomly allocated to receive a 3-month one-on-one, intensive lifestyle modification (intervention group (IG) n = 95) or standard guidance (control group (CG) n = 95). Participants completed questionnaires including demographic, dietary and physical activity data. Blood samples were collected at baseline, 3 and 6 months. A total of 123 (74 IG (age 40.6 ± 9.8 years; body mass index (BMI) 31.2 ± 7.0 kg/m(2)) and 49 CG (age 40.6 ± 12.7 years; BMI 32.3 ± 5.4 kg/m(2))) participants completed the study. After 6 months, haemoglobin A1c (HbA1c; primary endpoint) significantly improved in the IG than CG completers in between-group comparisons (p < 0.001). Comparison between groups showed significant improvements in overall energy intake, total and high density lipoprotein (HDL)-cholesterol in favour of IG (p-values < 0.001, 0.04 and <0.001, respectively). BMI and weight change were not clinically significant in between group comparisons. A 6-month, intense one-on-one intervention in lifestyle modification significantly improves glycaemic and cardio metabolic profile of females living in SA with pre-diabetes delivered in a primary care setting. Longer duration studies, using the same intervention, may determine whether a meaningful weight loss secondary to improved diet can be achieved. MDPI 2019-05-18 /pmc/articles/PMC6566809/ /pubmed/31109110 http://dx.doi.org/10.3390/nu11051113 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al-Hamdan, Rasha
Avery, Amanda
Salter, Andrew
Al-Disi, Dara
Al-Daghri, Nasser M.
McCullough, Fiona
Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes
title Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes
title_full Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes
title_fullStr Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes
title_full_unstemmed Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes
title_short Identification of Education Models to Improve Health Outcomes in Arab Women with Pre-Diabetes
title_sort identification of education models to improve health outcomes in arab women with pre-diabetes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566809/
https://www.ncbi.nlm.nih.gov/pubmed/31109110
http://dx.doi.org/10.3390/nu11051113
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