Thrombin Preconditioning Enhances Therapeutic Efficacy of Human Wharton’s Jelly–Derived Mesenchymal Stem Cells in Severe Neonatal Hypoxic Ischemic Encephalopathy

We investigated whether thrombin preconditioning of human Wharton’s jelly–derived mesenchymal stem cells (MSCs) improves paracrine potency and thus the therapeutic efficacy of naïve MSCs against severe hypoxic ischemic encephalopathy (HIE). Thrombin preconditioning significantly enhances the neuropr...

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Detalles Bibliográficos
Autores principales: Kim, Young Eun, Sung, Se In, Chang, Yun Sil, Ahn, So Yoon, Sung, Dong Kyung, Park, Won Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566845/
https://www.ncbi.nlm.nih.gov/pubmed/31137455
http://dx.doi.org/10.3390/ijms20102477

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