Development of a Bioluminescent BRCA1-Deficient Xenograft Model of Disseminated, High-Grade Serous Ovarian Cancer

Successful translation of preclinical data relies on valid and comprehensive animal models. While high-grade serous ovarian cancer (HGSOC) is the most prevalent subtype, the most commonly used ovarian cancer cell lines are not representative of HGSOC. In addition, 50% of ovarian cancer patients pres...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yen Ting, Wang, Lucy, Evans, James C., Allen, Christine, Piquette-Miller, Micheline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566953/
https://www.ncbi.nlm.nih.gov/pubmed/31117198
http://dx.doi.org/10.3390/ijms20102498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566953/
https://www.ncbi.nlm.nih.gov/pubmed/31117198
http://dx.doi.org/10.3390/ijms20102498

Ejemplares similares