Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway

Phloretin has pleiotropic effects, including glucose transporter (GLUT) inhibition. We previously showed that phloretin promoted adipogenesis of bone marrow stromal cell (BMSC) line ST2 independently of GLUT1 inhibition. This study investigated the effect of phloretin on osteoblastogenesis of ST2 ce...

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Detalles Bibliográficos
Autores principales: Takeno, Ayumu, Kanazawa, Ippei, Tanaka, Ken-ichiro, Notsu, Masakazu, Sugimoto, Toshitsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566987/
https://www.ncbi.nlm.nih.gov/pubmed/31137461
http://dx.doi.org/10.3390/ijms20102481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566987/
https://www.ncbi.nlm.nih.gov/pubmed/31137461
http://dx.doi.org/10.3390/ijms20102481

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