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Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases

Saffron is a natural compound that has been used for centuries in many parts of the world as a food colorant and additive. It was shown to have the ability to mitigate various disorders through its known anti-inflammatory and anti-oxidant properties. Several studies have shown the effectiveness of s...

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Autores principales: Ashktorab, Hassan, Soleimani, Akbar, Singh, Gulshan, Amin, Amr, Tabtabaei, Solmaz, Latella, Giovanni, Stein, Ulrike, Akhondzadeh, Shahin, Solanki, Naimesh, Gondré-Lewis, Marjorie C., Habtezion, Aida, Brim, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567082/
https://www.ncbi.nlm.nih.gov/pubmed/31027364
http://dx.doi.org/10.3390/nu11050943
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author Ashktorab, Hassan
Soleimani, Akbar
Singh, Gulshan
Amin, Amr
Tabtabaei, Solmaz
Latella, Giovanni
Stein, Ulrike
Akhondzadeh, Shahin
Solanki, Naimesh
Gondré-Lewis, Marjorie C.
Habtezion, Aida
Brim, Hassan
author_facet Ashktorab, Hassan
Soleimani, Akbar
Singh, Gulshan
Amin, Amr
Tabtabaei, Solmaz
Latella, Giovanni
Stein, Ulrike
Akhondzadeh, Shahin
Solanki, Naimesh
Gondré-Lewis, Marjorie C.
Habtezion, Aida
Brim, Hassan
author_sort Ashktorab, Hassan
collection PubMed
description Saffron is a natural compound that has been used for centuries in many parts of the world as a food colorant and additive. It was shown to have the ability to mitigate various disorders through its known anti-inflammatory and anti-oxidant properties. Several studies have shown the effectiveness of saffron in the treatment of various chronic diseases like inflammatory bowel diseases, Alzheimer’s, rheumatoid arthritis as well as common malignancies of the colon, stomach, lung, breast, and skin. Modern day drugs generally have unwanted side effects, which led to the current trend to use naturally occurring products with therapeutic properties. In the present review, the objective is to systematically analyze the wealth of information regarding the potential mechanisms of action and the medical use of saffron, the “golden spice”, especially in digestive diseases. We summarized saffron influence on microbiome, molecular pathways, and inflammation in gastric, colon, liver cancers, and associated inflammations.
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spelling pubmed-65670822019-06-17 Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases Ashktorab, Hassan Soleimani, Akbar Singh, Gulshan Amin, Amr Tabtabaei, Solmaz Latella, Giovanni Stein, Ulrike Akhondzadeh, Shahin Solanki, Naimesh Gondré-Lewis, Marjorie C. Habtezion, Aida Brim, Hassan Nutrients Communication Saffron is a natural compound that has been used for centuries in many parts of the world as a food colorant and additive. It was shown to have the ability to mitigate various disorders through its known anti-inflammatory and anti-oxidant properties. Several studies have shown the effectiveness of saffron in the treatment of various chronic diseases like inflammatory bowel diseases, Alzheimer’s, rheumatoid arthritis as well as common malignancies of the colon, stomach, lung, breast, and skin. Modern day drugs generally have unwanted side effects, which led to the current trend to use naturally occurring products with therapeutic properties. In the present review, the objective is to systematically analyze the wealth of information regarding the potential mechanisms of action and the medical use of saffron, the “golden spice”, especially in digestive diseases. We summarized saffron influence on microbiome, molecular pathways, and inflammation in gastric, colon, liver cancers, and associated inflammations. MDPI 2019-04-26 /pmc/articles/PMC6567082/ /pubmed/31027364 http://dx.doi.org/10.3390/nu11050943 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Ashktorab, Hassan
Soleimani, Akbar
Singh, Gulshan
Amin, Amr
Tabtabaei, Solmaz
Latella, Giovanni
Stein, Ulrike
Akhondzadeh, Shahin
Solanki, Naimesh
Gondré-Lewis, Marjorie C.
Habtezion, Aida
Brim, Hassan
Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases
title Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases
title_full Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases
title_fullStr Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases
title_full_unstemmed Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases
title_short Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases
title_sort saffron: the golden spice with therapeutic properties on digestive diseases
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567082/
https://www.ncbi.nlm.nih.gov/pubmed/31027364
http://dx.doi.org/10.3390/nu11050943
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