Cargando…
Discovery and antitumor evaluation of novel inhibitors of spermine oxidase
Increasing knowledge of the relationship between cancer and dysregulated polyamine catabolism suggests interfering with aberrant polyamine metabolism for anticancer therapy that will have considerable clinical promise. SMO (spermine oxidase) plays an essential role in regulating the polyamines homeo...
Autores principales: | Sun, Lidan, Yang, Jianlin, Qin, Yu, Wang, Yanlin, Wu, Hongyan, Zhou, You, Cao, Chunyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567099/ https://www.ncbi.nlm.nih.gov/pubmed/31159606 http://dx.doi.org/10.1080/14756366.2019.1621863 |
Ejemplares similares
-
SPERMINE OXIDASE: AN AMINE OXIDASE WITH SPECIFICITY FOR SPERMINE AND SPERMIDINE
por: Hirsch, James G.
Publicado: (1953) -
Identification of a Novel Substrate-Derived Spermine Oxidase Inhibitor
por: Dunston, T. T., et al.
Publicado: (2020) -
Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor
por: Diaz, Elsie, et al.
Publicado: (2022) -
434 In silico ADMET optimization and preliminary biologic activity of novel spermine oxidase inhibitors as neuroprotective agents
por: Furbish, Amelia B, et al.
Publicado: (2022) -
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase
por: Di Paolo, Maria Luisa, et al.
Publicado: (2019)