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Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer

All observational studies are liable to confounding and Levin’s formula becomes useless in practice for unbiasedly estimating PAF. With respect to causal interpretation of PAF in public health setting, unbiased estimation of PAF requires several assumptions which are ignored in practice. We recommen...

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Autores principales: Khosravi, Ahmad, Mansournia, Mohammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567379/
https://www.ncbi.nlm.nih.gov/pubmed/31196121
http://dx.doi.org/10.1186/s12940-019-0490-6
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author Khosravi, Ahmad
Mansournia, Mohammad Ali
author_facet Khosravi, Ahmad
Mansournia, Mohammad Ali
author_sort Khosravi, Ahmad
collection PubMed
description All observational studies are liable to confounding and Levin’s formula becomes useless in practice for unbiasedly estimating PAF. With respect to causal interpretation of PAF in public health setting, unbiased estimation of PAF requires several assumptions which are ignored in practice. We recommend using Miettinen PAF formula with careful consideration about possibility of bias in study design and analysis.
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spelling pubmed-65673792019-06-17 Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer Khosravi, Ahmad Mansournia, Mohammad Ali Environ Health Letter to the Editor All observational studies are liable to confounding and Levin’s formula becomes useless in practice for unbiasedly estimating PAF. With respect to causal interpretation of PAF in public health setting, unbiased estimation of PAF requires several assumptions which are ignored in practice. We recommend using Miettinen PAF formula with careful consideration about possibility of bias in study design and analysis. BioMed Central 2019-06-13 /pmc/articles/PMC6567379/ /pubmed/31196121 http://dx.doi.org/10.1186/s12940-019-0490-6 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Khosravi, Ahmad
Mansournia, Mohammad Ali
Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer
title Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer
title_full Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer
title_fullStr Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer
title_full_unstemmed Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer
title_short Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer
title_sort issues with incorrect computing of population attributable fraction (paf) in a global perspective on coal-fired power plants and burden of lung cancer
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567379/
https://www.ncbi.nlm.nih.gov/pubmed/31196121
http://dx.doi.org/10.1186/s12940-019-0490-6
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