CASSETTE—clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: study protocol for a randomised controlled trial

BACKGROUND: Exotoxins are important virulence factors in Staphylococcus aureus. Clindamycin, a protein synthesis inhibitor antibiotic, is thought to limit exotoxin production and improve outcomes in severe S. aureus infections. However, randomised prospective data to support this are lacking. METHOD...

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Detalles Bibliográficos
Autores principales: Dotel, Ravindra, Tong, Steven Y. C., Bowen, Asha, Nelson, Jane N., O’Sullivan, Matthew V. N., Campbell, Anita J., McMullan, Brendan J., Britton, Philip N., Francis, Joshua R., Eisen, Damon P., Robinson, Owen, Manning, Laurens, Davis, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567404/
https://www.ncbi.nlm.nih.gov/pubmed/31196132
http://dx.doi.org/10.1186/s13063-019-3452-y

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