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Towards creating an extended metabolic model (EMM) for E. coli using enzyme promiscuity prediction and metabolomics data
BACKGROUND: Metabolic models are indispensable in guiding cellular engineering and in advancing our understanding of systems biology. As not all enzymatic activities are fully known and/or annotated, metabolic models remain incomplete, resulting in suboptimal computational analysis and leading to un...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567437/ https://www.ncbi.nlm.nih.gov/pubmed/31196115 http://dx.doi.org/10.1186/s12934-019-1156-3 |