Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis

OBJECTIVE: The study was dedicated to investigation of some hemostasis and endothelial dysfunction factors association with probability of presence of vulnerable atherosclerotic plaques in coronary arteries in men with atherosclerosis. RESULTS: The blood levels of factor VII, factor XII and MCP-1 we...

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Autores principales: Ragino, Yu. I., Striukova, E. V., Murashov, I. S., Polonskaya, Ya. V., Volkov, A. M., Kurguzov, A. V., Chernjavskii, A. M., Kashtanova, E. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567509/
https://www.ncbi.nlm.nih.gov/pubmed/31196144
http://dx.doi.org/10.1186/s13104-019-4360-7
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author Ragino, Yu. I.
Striukova, E. V.
Murashov, I. S.
Polonskaya, Ya. V.
Volkov, A. M.
Kurguzov, A. V.
Chernjavskii, A. M.
Kashtanova, E. V.
author_facet Ragino, Yu. I.
Striukova, E. V.
Murashov, I. S.
Polonskaya, Ya. V.
Volkov, A. M.
Kurguzov, A. V.
Chernjavskii, A. M.
Kashtanova, E. V.
author_sort Ragino, Yu. I.
collection PubMed
description OBJECTIVE: The study was dedicated to investigation of some hemostasis and endothelial dysfunction factors association with probability of presence of vulnerable atherosclerotic plaques in coronary arteries in men with atherosclerosis. RESULTS: The blood levels of factor VII, factor XII and MCP-1 were higher, and concentration of sVCAM-1 lower in men with vulnerable atherosclerotic plaques in the coronary arteries, compared to men who had stable plaques. Have been revealed correlation links between the blood levels of factor II, factor XII, MCP-1 and the presence of vulnerable atherosclerotic plaques in the coronary arteries. Results of logistic regression analysis showed that the relative risk of present of vulnerable atherosclerotic plaques in the coronary arteries is associated with an elevated blood level of factor XII and MCP-1.
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spelling pubmed-65675092019-06-17 Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis Ragino, Yu. I. Striukova, E. V. Murashov, I. S. Polonskaya, Ya. V. Volkov, A. M. Kurguzov, A. V. Chernjavskii, A. M. Kashtanova, E. V. BMC Res Notes Research Note OBJECTIVE: The study was dedicated to investigation of some hemostasis and endothelial dysfunction factors association with probability of presence of vulnerable atherosclerotic plaques in coronary arteries in men with atherosclerosis. RESULTS: The blood levels of factor VII, factor XII and MCP-1 were higher, and concentration of sVCAM-1 lower in men with vulnerable atherosclerotic plaques in the coronary arteries, compared to men who had stable plaques. Have been revealed correlation links between the blood levels of factor II, factor XII, MCP-1 and the presence of vulnerable atherosclerotic plaques in the coronary arteries. Results of logistic regression analysis showed that the relative risk of present of vulnerable atherosclerotic plaques in the coronary arteries is associated with an elevated blood level of factor XII and MCP-1. BioMed Central 2019-06-13 /pmc/articles/PMC6567509/ /pubmed/31196144 http://dx.doi.org/10.1186/s13104-019-4360-7 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Ragino, Yu. I.
Striukova, E. V.
Murashov, I. S.
Polonskaya, Ya. V.
Volkov, A. M.
Kurguzov, A. V.
Chernjavskii, A. M.
Kashtanova, E. V.
Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
title Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
title_full Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
title_fullStr Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
title_full_unstemmed Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
title_short Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
title_sort association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567509/
https://www.ncbi.nlm.nih.gov/pubmed/31196144
http://dx.doi.org/10.1186/s13104-019-4360-7
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