Elevated level of mitochondrial reactive oxygen species via fatty acid β-oxidation in cancer stem cells promotes cancer metastasis by inducing epithelial–mesenchymal transition

BACKGROUND: Cancer stem cells (CSCs) play a critical role in tumor development and progression and are involved in cancer metastasis. The role of reactive oxygen species (ROS) in CSCs and cancer metastasis remains controversial. The aim of the present study was to investigate the correlation between...

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Detalles Bibliográficos
Autores principales: Wang, Caihua, Shao, Liming, Pan, Chi, Ye, Jun, Ding, Zonghui, Wu, Jia, Du, Qin, Ren, Yuezhong, Zhu, Chunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567550/
https://www.ncbi.nlm.nih.gov/pubmed/31196164
http://dx.doi.org/10.1186/s13287-019-1265-2

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