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Mitral valve repair: moving towards a personalized ring

BACKGROUND: Mitral valve repair with the use of an annuloplasty ring is the procedure of choice in patients with significant mitral regurgitation (MR) due to floppy mitral valve (FMV)/mitral valve prolapse (MVP). The mitral annular size, shape and motion may vary substantially among patients and thu...

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Autores principales: Pitsis, Antonios, Kelpis, Timotheos, Theofilogiannakos, Efstratios, Tsotsolis, Nikolaos, Boudoulas, Harisios, Boudoulas, Konstantinos Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567592/
https://www.ncbi.nlm.nih.gov/pubmed/31196216
http://dx.doi.org/10.1186/s13019-019-0926-7
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author Pitsis, Antonios
Kelpis, Timotheos
Theofilogiannakos, Efstratios
Tsotsolis, Nikolaos
Boudoulas, Harisios
Boudoulas, Konstantinos Dean
author_facet Pitsis, Antonios
Kelpis, Timotheos
Theofilogiannakos, Efstratios
Tsotsolis, Nikolaos
Boudoulas, Harisios
Boudoulas, Konstantinos Dean
author_sort Pitsis, Antonios
collection PubMed
description BACKGROUND: Mitral valve repair with the use of an annuloplasty ring is the procedure of choice in patients with significant mitral regurgitation (MR) due to floppy mitral valve (FMV)/mitral valve prolapse (MVP). The mitral annular size, shape and motion may vary substantially among patients and thus, commercially available rings may not be suitable for each individual patient. METHODS: A “personalized ring” (PR) was easily constructed in the operating room using a Dacron sheet and titanium ligating clips to custom fit to each individual mitral annulus shape and size. There were 127 patients with severe MR due to FMV/MVP that underwent mitral valve repair surgery; 58 patients received a PR and 69 patients received a commercial Carpentier-Edwards Physio II ring. The patient records were retrospectively analysed. RESULTS: There were no surgical deaths. In-hospital length-of-stay and blood transfusions were not statistically different between the two groups. Mitral valve area was greater (p < 0.05) in the PR group (3.78 ± 0.22) compared to the Physio II ring group (3.13 ± 0.21). Mitral annular area changed from systole to diastole by 14.35% ± 3.28% in the PR group and did not change in the Physio II ring group (p < 0.05). Systolic anterior motion (SAM) of the mitral valve occurred in 2 patients with the Physio II ring and no patients with the PR. Up to 8 years follow-up, all patients in both groups were alive with NYHA functional class I-II symptoms and mild or less MR. CONCLUSIONS: The PR is suitable for all patients with significant MR due to FMV/MVP who require MV repair. The precise fit of the PR to the mitral annulus better preserves valve area and sphincter function of the mitral annulus, prevents SAM and provides excellent short and long-term results.
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spelling pubmed-65675922019-06-17 Mitral valve repair: moving towards a personalized ring Pitsis, Antonios Kelpis, Timotheos Theofilogiannakos, Efstratios Tsotsolis, Nikolaos Boudoulas, Harisios Boudoulas, Konstantinos Dean J Cardiothorac Surg Research Article BACKGROUND: Mitral valve repair with the use of an annuloplasty ring is the procedure of choice in patients with significant mitral regurgitation (MR) due to floppy mitral valve (FMV)/mitral valve prolapse (MVP). The mitral annular size, shape and motion may vary substantially among patients and thus, commercially available rings may not be suitable for each individual patient. METHODS: A “personalized ring” (PR) was easily constructed in the operating room using a Dacron sheet and titanium ligating clips to custom fit to each individual mitral annulus shape and size. There were 127 patients with severe MR due to FMV/MVP that underwent mitral valve repair surgery; 58 patients received a PR and 69 patients received a commercial Carpentier-Edwards Physio II ring. The patient records were retrospectively analysed. RESULTS: There were no surgical deaths. In-hospital length-of-stay and blood transfusions were not statistically different between the two groups. Mitral valve area was greater (p < 0.05) in the PR group (3.78 ± 0.22) compared to the Physio II ring group (3.13 ± 0.21). Mitral annular area changed from systole to diastole by 14.35% ± 3.28% in the PR group and did not change in the Physio II ring group (p < 0.05). Systolic anterior motion (SAM) of the mitral valve occurred in 2 patients with the Physio II ring and no patients with the PR. Up to 8 years follow-up, all patients in both groups were alive with NYHA functional class I-II symptoms and mild or less MR. CONCLUSIONS: The PR is suitable for all patients with significant MR due to FMV/MVP who require MV repair. The precise fit of the PR to the mitral annulus better preserves valve area and sphincter function of the mitral annulus, prevents SAM and provides excellent short and long-term results. BioMed Central 2019-06-13 /pmc/articles/PMC6567592/ /pubmed/31196216 http://dx.doi.org/10.1186/s13019-019-0926-7 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Pitsis, Antonios
Kelpis, Timotheos
Theofilogiannakos, Efstratios
Tsotsolis, Nikolaos
Boudoulas, Harisios
Boudoulas, Konstantinos Dean
Mitral valve repair: moving towards a personalized ring
title Mitral valve repair: moving towards a personalized ring
title_full Mitral valve repair: moving towards a personalized ring
title_fullStr Mitral valve repair: moving towards a personalized ring
title_full_unstemmed Mitral valve repair: moving towards a personalized ring
title_short Mitral valve repair: moving towards a personalized ring
title_sort mitral valve repair: moving towards a personalized ring
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567592/
https://www.ncbi.nlm.nih.gov/pubmed/31196216
http://dx.doi.org/10.1186/s13019-019-0926-7
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