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Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice
BACKGROUND: Treatment with the α-glucosidase inhibitor acarbose increases median lifespan by approximately 20% in male mice and 5% in females. This longevity extension differs from dietary restriction based on a number of features, including the relatively small effects on weight and the sex-specifi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567620/ https://www.ncbi.nlm.nih.gov/pubmed/31195972 http://dx.doi.org/10.1186/s12866-019-1494-7 |