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Prediction of activity and specificity of CRISPR-Cpf1 using convolutional deep learning neural networks
BACKGROUND: CRISPR-Cpf1 has recently been reported as another RNA-guided endonuclease of class 2 CRISPR-Cas system, which expands the molecular biology toolkit for genome editing. However, most of the online tools and applications to date have been developed primarily for the Cas9. There are a limit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567654/ https://www.ncbi.nlm.nih.gov/pubmed/31195957 http://dx.doi.org/10.1186/s12859-019-2939-6 |