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Aplnra/b Sequentially Regulate Organ Left-Right Patterning via Distinct Mechanisms
The G protein-coupled receptor APJ/Aplnr has been widely reported to be involved in heart and vascular development and disease, but whether it contributes to organ left-right patterning is largely unknown. Here, we show that in zebrafish, aplnra/b coordinates organ LR patterning in an apela/apln lig...
Autores principales: | Zhu, Chengke, Guo, Zhenghua, Zhang, Yu, Liu, Min, Chen, Bingyu, Cao, Kang, Wu, Yongmei, Yang, Min, Yin, Wenqing, Zhao, Haixia, Tai, Haoran, Ou, Yu, Yu, Xiaoping, Liu, Chi, Li, Shurong, Su, Bingyin, Feng, Yi, Huang, Sizhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567806/ https://www.ncbi.nlm.nih.gov/pubmed/31223282 http://dx.doi.org/10.7150/ijbs.30100 |
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