Biological Rationale for Targeting MEK/ERK Pathways in Anti-Cancer Therapy and to Potentiate Tumour Responses to Radiation

ERK1 and ERK2 (ERKs), two extracellular regulated kinases (ERK1/2), are evolutionary-conserved and ubiquitous serine-threonine kinases involved in regulating cell signalling in normal and pathological tissues. The expression levels of these kinases are almost always different, with ERK2 being the mo...

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Detalles Bibliográficos
Autores principales: Marampon, Francesco, Ciccarelli, Carmela, Zani, Bianca Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567863/
https://www.ncbi.nlm.nih.gov/pubmed/31126017
http://dx.doi.org/10.3390/ijms20102530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567863/
https://www.ncbi.nlm.nih.gov/pubmed/31126017
http://dx.doi.org/10.3390/ijms20102530

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