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Inhibition of mPGES-1 or COX-2 Results in Different Proteomic and Lipidomic Profiles in A549 Lung Cancer Cells
Pharmacological inhibition of microsomal prostaglandin E synthase (mPGES)-1 for selective reduction in prostaglandin E(2) (PGE(2)) biosynthesis is protective in experimental models of cancer and inflammation. Targeting mPGES-1 is envisioned as a safer alternative to traditional non-steroidal anti-in...
Autores principales: | Bergqvist, Filip, Ossipova, Elena, Idborg, Helena, Raouf, Joan, Checa, Antonio, Englund, Karin, Englund, Petter, Khoonsari, Payam Emami, Kultima, Kim, Wheelock, Craig E., Larsson, Karin, Korotkova, Marina, Jakobsson, Per-Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567928/ https://www.ncbi.nlm.nih.gov/pubmed/31231223 http://dx.doi.org/10.3389/fphar.2019.00636 |
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