Diketopyrrolopyrrole-based fluorescence probes for the imaging of lysosomal Zn(2+) and identification of prostate cancer in human tissue

A series of diketopyrrolopyrrole-based fluorescent probes (DPP-C2, LysoDPP-C2, LysoDPP-C3, and LysoDPP-C4) have been developed for the detection of low pH and Zn(2+) in an AND logic fashion. The chelation of Zn(2+) or the protonation of a morpholine moiety within these probes results in a partial in...

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Detalles Bibliográficos
Autores principales: Du, Chenchen, Fu, Shibo, Wang, Xiaohua, Sedgwick, Adam C., Zhen, Wei, Li, Minjie, Li, Xinqiang, Zhou, Juan, Wang, Zhong, Wang, Hongyu, Sessler, Jonathan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568042/
https://www.ncbi.nlm.nih.gov/pubmed/31293754
http://dx.doi.org/10.1039/c9sc01153f

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