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Laser Capture Microdissection and RNA-Seq Analysis: High Sensitivity Approaches to Explain Histopathological Heterogeneity in Human Glioblastoma FFPE Archived Tissues

Laser capture microdissection (LCM) coupled with RNA-seq is a powerful tool to identify genes that are differentially expressed in specific histological tumor subtypes. To better understand the role of single tumor cell populations in the complex heterogeneity of glioblastoma, we paired microdissect...

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Detalles Bibliográficos
Autores principales: Civita, Prospero, Franceschi, Sara, Aretini, Paolo, Ortenzi, Valerio, Menicagli, Michele, Lessi, Francesca, Pasqualetti, Francesco, Naccarato, Antonio Giuseppe, Mazzanti, Chiara Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568189/
https://www.ncbi.nlm.nih.gov/pubmed/31231613
http://dx.doi.org/10.3389/fonc.2019.00482